It’s in the blood – Eosinophilic Asthma

After a recent follow-up outpatient appointment I was informed that blood works showed I have Eosinophilic Asthma, I am a unique breed that have managed to develop this rare condition found only in adults aged between 35 – 65 years.

So what is Eosinophilic asthma?

Well, for many years asthma has always been thought of as a single condition, however in recent years medical advancements and different studies have concluded that there are several different strands within the condition.

Eosinophilic asthma is another strand, it is a rare type of asthma, from my understanding (please note I have no medical knowledge and this is purely my view) it has to do with the white blood cells.

One way in which the white blood cells fight disease in our body is by swelling, this is usually beneficial for us, however when it swells the airways this is when problems occur.

Your heart starts beating faster (tachycardia) this moves more blood around which have more white cells thus increasing the rate of swelling, this lead to a severe exacerbation of breathing.

Your normal inhalers will not be as active as the restriction is being caused by the blood not an external trigger, when presented to doctors your vitals will be deemed in the safe zone, your oxygen levels will be good, your airways will sound restricted but have good movement, your blood cultures will show no infections, so on paper your are not having a normal asthma attack but breathing issues which may be diagnosed as a panick attack.

This means the asthma is harder to identify, and more importantly manage, it has a profound impact on the quality of life, there are treatments corticosteroid pills, which can have more side effects than an inhaler, biologics have been found to be effective in reducing the frequency of eosinophilic asthma attacks. These include:

  • Benralizumab (Fasenra)
  • Mepolizumab (Nucala)
  • Reslizumab (Cinqair)

I have a consultation next week at the Brompton to discuss Mepolizumab, which I am very excited about and will report back once I start the treatment. The drug is injected and changes the way the immune system fights, this will help reduce the chances of the swelling in the airways and allow the white blood cells to work within their normal limits.

I have been rejected for similar treatments in the past due to high IgE levels, lets hope I am applicable for this treatment. I shall report to you soon.

Take a breathe,

Raj

 

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